Principle Microbiology

Vaccines are any preparation which are made up of either whole microorganisms, macromolecules of microorganisms, DNAs or Recombinant Vector which can induce immunity in the host animal when given to it.

Vaccines are produced in many ways, most traditional of which is the embryonated hen's egg technique. But nowadays the place of embryonated hen's egg is being taken by the use of animal cell lines. Animal cell lines have various advantages over the other traditional techniques. Moreover animal cell lines also overcome some of the traditional problems faced during older techniques. There are also some limitations of the use of animal cell lines.

The whole article on the Use of animal cell lines in vaccine production can be read here as a powerpoint presentation on Google documents.

http://docs.google.com/leaf?id=0B0c57-C3kwyuOTdkZGVmZjMtZDA2YS00YjU4LTk2ZmYtZDY1NDg0YjU0ZTkz&hl=en

It contains following points...

What is a Vaccine?
Historical notes
Types of vaccines
Why cell lines?
Potential advantages
Ideal characteristics of cell lines used in vaccine production
Considerations Related to Specific Cell Lines
Production steps

I hope this article and the powerpoint helps you in one or another way...

- TRUNAL YATINDRA GUPTE